From a microbiological point of view, the product should be used immediately. Forms available from special-order manufacturers include: The most serious hazard of therapy is respiratory depression although circulatory depression is also possible. If affected patients should not drive or use machines This medicine can impair cognitive function and can affect a patient’s ability to drive safely. Nerve blocks or regional anaesthesia techniques including the use of epidural and intrathecal catheters can be considered when pain is localised to a specific area. To email a medicine you must sign up and log in.

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The dose should be suited to the individual patient.

Diamorphine is a narcotic analgesic which acts primarily on the central nervous system and smooth muscle. Confusion and restlessness Haloperidol has little sedative effect.

Great caution should be exercised diamorpine patients with a known tendency or history of drug abuse. Respiratory depression, pulmonary oedema, muscle flaccidity, coma or stupor, constricted pupils, cold, clammy skin and occasionally bradycardia and hypotension. Diamorphine may be used in the treatment of severe pain associated with surgical procedures, myocardial infarction or pain in the terminally ill and for the relief of dyspnoea in acute pulmonary oedema.

Oxycodone hydrochloride can be used in patients who require an opioid but cannot tolerate morphine.

To bookmark a medicine you must sign up and log in. Cyclizine is particularly likely to precipitate if mixed with diamorphine or other drugs see under Mixing and Compatibility, below. Continuous subcutaneous infusion should be monitored regularly both to check for precipitation and discoloration and to ensure that the infusion is running at the correct rate.

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Each ampoule contains mg of Diamorphine Hydrochloride BP. The dose and duration of concomitant use should be limited see section 4. Headache due to raised intracranial pressure often responds to a high dose of a corticosteroid, such as dexamethasone and should be given before 6 p. By intramuscular injection, or by subcutaneous injection.

Metoclopramide hydrochloride can cause skin reactions. Breathlessness at rest may be relieved by regular oral morphine in carefully titrated doses. Continue typing to refine. Gastro-intestinal pain The pain of bowel colic may be reduced by loperamide hydrochloride.

Diamorphine Hydrochloride BP 100 mg Lyophilisate for Solution for Injection

The first dose of the modified-release preparation is given with, or within 4 hours of, the last dose of the immediate-release preparation. Show table of contents Hide dosae of contents 1.

For the treatment of nausea and vomiting associated with cancer chemotherapy see Cytotoxic drugs. Hospice care of terminally ill patients has shown the importance of symptom control and psychosocial support of the patient and family.

If symptoms persist, they can be given regularly via a continuous infusion device. If a decision is made to prescribe diamorphine concomitantly with sedative medicines, the lowest effective dose should be used, and the duration of treatment should be as short as possible. Ideally, the cause should be determined before treatment with an antiemetic is started.

The analgesic effect lasts approximately three to four hours. Bowel colic and excessive respiratory secretions Bowel colic and excessive respiratory secretions syrinhe be reduced by a subcutaneous injection of hyoscine hydrobromidehyoscine butylbromideor glycopyrronium bromide. In the case of obstructive jaundice, further measures include administration of colestyramine.


Prescribing in palliative care | Medicines guidance | BNF content published by NICE

Bowel colic and excessive respiratory secretions may be reduced by a subcutaneous injection of hyoscine hydrobromidehyoscine butylbromideor glycopyrronium bromide. Dexamethasonespecial care is needed to avoid precipitation of dexamethasone when preparing it. Nausea and vomiting Haloperidol and levomepromazine can both be given as a subcutaneous infusion but sedation can limit the dose of levomepromazine. Sign Up Log In Cancel.

Bowel colic and excessive respiratory secretions Hyoscine hydrobromide effectively reduces respiratory secretions and bowel colic and is sedative but occasionally causes paradoxical agitation.

Name of the medicinal product 2. Drug treatment The number of drugs should be as few as possible, for even the taking of medicine may be an effort.

Capillary bleeding Capillary bleeding can be treated with tranexamic acid by mouth; treatment is usually discontinued one week after the bleeding has stopped, or, if necessary, it can be continued at a reduced dose.